Adult Craniopharyngiomas. Differences and Lessons from Paediatrics

Description:

This volume focuses on adult craniopharyngiomas, offering various perspectives. The first part of the book provides an up-to-date overview of the pathogenesis and management of adult craniopharyngiomas, helping readers understand the pathogenesis and molecular pathways. It highlights the importance of animal models for addressing molecular keys and for developing targeted therapies. The second part deals with clinical management, detailing the latest results in the era of endoscopic surgery, including the major contribution of the extended nasal endoscopic approaches for suprasellar and retrochiasmatic tumors. The book also discusses the key aspects of these tumors and how to manage them. The last part of the book addresses the future therapies and recurrences after surgery and radiotherapy. This volume is of interest to neurosurgeons, endocrinologists, paediatricians, radiologists and oncologists.

Table of Contents:

1. Histopathology and Molecular Pathology of Craniopharyngioma in Adults

2. Mouse Models of Craniopharyngioma

3. Epidemiology, Clinical Presentation, and Prognosis of Adult-Onset Craniopharyngioma

4. Craniopharyngioma Diagnosis: A Rationale for Accurate MRI Assessment of Tumor Topography and Adhesion to the Hypothalamus

5. How Far with Surgery in the Modern Era of Endoscopy: Nasal Route

6. Cranial Surgery for Adult Craniopharyngiomas: Techniques and Indications

7. Definitive Radiotherapy in Adult Population Craniopharyngiomas

8. How to Manage Recurrent Craniopharyngiomas

9. Craniopharyngioma: Endocrinological Aspects After Surgery

10. Disease and Treatment-Related Hypothalamic Alterations in Craniopharyngioma: Clinical Presentation, Prognostic Impact, and Implications for Treatment Strategies

11. Adult Versus Paediatric Craniopharyngiomas: Which Differences?

12. Molecular Targets in Craniopharyngioma

13. Conclusions