Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging

Features:

• Covers different aspects of anti-aging research, from foundational knowledge to future perspectives
• Provides understanding on the different hallmarks of aging and how they can be applied in the development of anti-aging drugs
• Discusses various anti-aging strategies, including telomerase reactivation, clearance of senescent cells, stem cell-based therapy, and others

Table Of Contents:

1. The aging: introduction, theories, principles and future prospective
Shabnam Shabir, Mahendra Pratap Singh

2. Brief description of aging in different levels as cellular, tissues, and organs
Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Amit Singh

3. Brief about hallmarks of aging
Josephine Esposto and Vyshnavy Balendra

4. Overview of various anti-aging strategies
Dhiraj Kumar and Faiyaz Ahmad

5. Elimination of damaged cells-dependent anti-aging strategy
Rayees Ahmad Naik, Vinodinee Dubey, Roshni Rajpoot, Debabrata Dash, Nidhi Gupta and Raj Kumar Koiri

6. Telomerase reactivation for anti-aging
TS Gopenath, Shreya Shreshtha and Kanthesh M. Basalingapa

7. Epigenetic drugs based on anti-aging approach
Tarun Minocha, Namrata Dwivedi, Chetan Panda, Anamika Misra, Barsha Baisakhi Nayak, Sanjeev Kumar Yadav, Hareram Birla and Sandeep K. Singh

8. Activation of chaperons and proteolytic system: emerging methods for anti-aging drug development
Neha Gogia, Victor Olmos, Fatema Haidery, Kimberly Luttik, Leon Tejwani, Janghoo Lim

9. Dietary restriction and mTOR and IIS inhibition: the potential to anti-aging drug approach
Sing-Hua Tsou

10. Anti-Aging Drugs, Candidates, and Food Supplements- The journey so far
Yodhaanjali JR, Rithwick Surya, Sumukha KC, Harini G, Gouri Deshpande, Chandan S,Raghu Ram Achar

11. Role of AMPK and Sirtuins as anti-aging proteins
Manjula Ramu, Sonali Vishal and Neha Gogia

12. Mitophagy and Mitohormetics: promising anti- aging strategy
Chih Li Lin

13. Clearance of senescent cells: potent anti-aging approach
Jacques Ferreira and Alex Deamer

14. Stem cell-based therapy as antiaging prospective
Sumaira Yusuf, Mahendra P. Singh

15. Anti-inflammatory therapy as a game changer towards anti-aging
Dr. Naveen Shivavedi, Anshul Shakya, Bedanta Bhattacharjee and Bhargab Deka

16. Invertebrate model organisms for aging research
Arvind Kumar Shukla, Andrew Scott and Edward Giniger