Concepts and Principles of Pharmacology: 100 Years of the Handbook of Experimental Pharmacology: 260

 

Description:

Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

 

 

 

Table of Contents:

 

1.    

2.     Emergent Concepts of Receptor Pharmacology

3.     The Evolving Landscape of Cancer Therapeutics

4.     Monoclonal Antibodies: Past, Present and Future

5.     100 Years of Drug Delivery to the Lungs

6.     Ion Channel Pharmacology for Pain Modulation

7.     Exploiting the Diversity of Ion Channels: Modulation of Ion Channels for Therapeutic Indications

8.     Genetically Encoded Fluorescent Calcium and Voltage Indicators

9.     Mechanistic Image-Based Modelling: Concepts and Applications

10.   Pharmacometabonomics: The Prediction of Drug Effects Using Metabolic Profiling

11.   The Microbiome and Its Potential for Pharmacology

12.   Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology

13.   The Future of Clinical Trial Design: The Transition from Hard Endpoints to Value-Based Endpoints

14.   Placebos and the Placebo Effect in Drug Trials

15.   Pharmacoepidemiology

16.   Why Are New Drugs Expensive and How Can They Stay Affordable?