Description:
Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years.
These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies.
Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
Table of Contents:
Perspectives of Pharmacology over the Past 100 Years
Emergent Concepts of Receptor Pharmacology
The Evolving Landscape of Cancer Therapeutics
Monoclonal Antibodies: Past, Present and Future
100 Years of Drug Delivery to the Lungs
Ion Channel Pharmacology for Pain Modulation
Exploiting the Diversity of Ion Channels: Modulation of Ion Channels for Therapeutic Indications
Genetically Encoded Fluorescent Calcium and Voltage Indicators
Mechanistic Image-Based Modelling: Concepts and Applications
Pharmacometabonomics: The Prediction of Drug Effects Using Metabolic Profiling
The Microbiome and Its Potential for Pharmacology
Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology
The Future of Clinical Trial Design: The Transition from Hard Endpoints to Value-Based Endpoints
Placebos and the Placebo Effect in Drug Trials
Pharmacoepidemiology
Why Are New Drugs Expensive and How Can They Stay Affordable?
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