Dermatokinetics of Therapeutic Agents

Novel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity.

?

€€The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass.

The dermatokinetics of a drug determines the efficacy of treatment of skin disorders.

Presenting the first comprehensive reference on this important area of research, Dermatokinetics of Therapeutic Agents includes a general overview of the theoretical as well as practical aspects of dermatokinetics and addresses the impact of a drug delivery system on the dermatokinetics of drugs.

Chapters and illustrations cover introductory aspects and the significance, methods, and models used in dermatokinetic studies of therapeutic agents.

Topics include:

• Theoretical Models for Dermatokinetics of Therapeutic Agents
• Drug Delivery Approaches to Modulate Dermatokinetics of Drugs
• Conventional Methods of Cutaneous Drug Sampling
• Cutaneous Microdialysis
• Sampling Substrates by Skin Permeabilization
• Spectroscopic Techniques in Dermatokinetics Studies
• Regulatory Perspective of Dermatokinetic Studies