Handbook of Diagnostic Endocrinology

Description

The clinical laboratory plays a critical role in the diagnosis and management of endocrine and related metabolic disorders, which are leading causes of morbidity and mortality in children and adults. The Handbook of Diagnostic Endocrinology, Third Edition, provides a ready reference for the evaluation, diagnosis, and monitoring of such disorders. This revision incorporates translational medicine, connecting what clinicians need to know with those in research providing a clinical context to which they can relate their molecular findings. This book solves the needs of clinicians and researchers by bringing together in one book endocrinology at the molecular and clinical levels. As the intricacies of intracellular signaling have become better understood, states of hormone resistance are now increasingly recognized. The most common endocrinopathy in westernized countries, the metabolic syndrome, results, to a large extent, from insulin resistance. The complexity of the circulating forms of various hormones are acknowledged in this revision.

Key Features

Each chapter focuses on the biochemical tests that are required, either in the basal state or following provocation or suppression, to assist in the diagnosis of the various disorders

Describes proper sample collection and relevant interpretations of laboratory tests

Contains essential molecular biology and incorporates it with the clinical information

Includes the discovery of new diagnostic and treatment methods

Readership

Clinical chemists, chemical pathologists, endocrinologists, and senior medical technologists to aid them in the investigation of endocrine and metabolic disorders

Table of Contents

Maximizing the value of laboratory tests
Raffick A.R. Bowen, Roger L. Bertholf and Brett Holmquist

2. Laboratory investigation of disorders of the pituitary gland
Verena Gounden, Charlotte C. Ellberg and Ishwarlal Jialal

3. Thyroid disease and laboratory assessment
Sridevi Devaraj and Emily Garnett

4. Disorders of the adrenal gland
Roger L. Bertholf

5. Endocrine disorders of the reproductive system
Angela M. Ferguson and Mark A. Cervinski

6. Gastroenteropancreatic tumors
Neeraj Ramarishnan, Seong Hyun Ahn and Ishwarlal Jialal

7. Evaluation of hypoglycemia
William E. Winter and Neil S. Harris

8. Evaluation of hyperglycemia
William E. Winter, David L. Pittman, Sridevi Devaraj, Danni Li and Neil S. Harris

9. Lipoproteins
Anna Wolska and Alan T. Remaley

10. Disorders of calcium metabolism
William E. Winter and Neil S. Harris

11. Laboratory evaluation of endocrine hypertension
William E. Winter and Neil S. Harris

12. Malignancy-associated endocrine disorders
Lori J. Sokoll and Daniel W. Chan

13. Laboratory assessment of acquired immunodeficiency syndrome endocrinopathies
Verena Gounden and Manisha Chandalia

14. Laboratory evaluation of short stature in children
William E. Winter

15. Pregnancy and the fetus
K. Aaron Geno, Mark A. Cervinski and Robert D. Nerenz

16. Disorders of sexual development
William E. Winter, Paul Hiers and Dina N. Greene

17. Transgender endocrinology
Dina N. Greene, Tamar Reisman and Zil Goldstein

18. The endocrinology of aging
Daniel T. Holmes and Gregory Kline