Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications

Features: •Summarizes current liver regeneration studies and discussions on expected discoveries. •Provides an overview of standard scientific and cutting-edge technologies to study liver regeneration. •Presents details on the molecular mechanisms that affect liver regeneration. •Highly illustrated to make the text easier to interpret. Table Of Contents: Chapter

1. Introduction to Liver Regeneration: History and General Principles Chapter

2. Models to Study Liver Regeneration Chapter

3. Alternative Models to Study Liver Regeneration: Zebrafish Chapter

4. The Priming and Progression Theory of Liver Regeneration Chapter

5. Primary and Secondary Mitogen Theory of Liver Regeneration Chapter

6. Developmental Pathways in Liver Regeneration Chapter

7. Mechanisms of Termination of Liver Regeneration Chapter

8. Modulation of Extracellular Matrix During Liver Regeneration Chapter

9. Role of Chemokines Chapter

10. Role of Nuclear Receptors Chapter

11. Role of Developmental Morphogens in Liver Regeneration Chapter

12. Regulation of Cell Cycle during Liver Regeneration Chapter

13. Role of microRNAs and Long Non-Coding RNAs in Liver Regeneration Chapter

14. Changes in Hepatocyte Ploidy during Liver Regeneration Chapter

15. Role of Endothelial cells in Liver Regeneration Chapter

16. Use of Computational Biology, Omics Technologies to Understand Liver Regeneration Chapter

17. Mitogen Induced Cell Proliferation in the Liver Chapter

18. Effect of Nutritional Diversity on Liver Regeneration Chapter

19. Introduction of Hepatic Progenitor Cells Chapter

20. Cellular Transdifferentiation in the Liver Chapter

21. Activation of Hepatic Progenitor Cells in Liver Regeneration After Chemical Injury to the Liver Chapter

22. Hepatic Progenitor Cells and iPS Cells as a source of Mature Hepatocytes Chapter

23. Progenitor Cell Transplantation: Experimental Models Chapter

24. Liver Regeneration as a Therapy for Acute Liver Failure Chapter

25. Liver Regeneration following Liver Transplantation Chapter

26. Hepatocyte Transplantation Therapy Chapter

27. Liver Regeneration: The Biliary Perspective.

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