Microbiome in Gastrointestinal Cancer

 

Description:

This book covers state-of-the-art topics covering evidences indicate that the gut microbiota can be harnessed for cancer prevention as well as to modulate the efficacy of chemotherapy and immunotherapy.

This book includes: 1) characterization of the dysregulated microbiome in gastrointestinal cancers (Chapters 1-6); 2) the molecular mechanism of action of gut microbiota via microbial metabolites and direct interaction with host cancer or immune cells (Chapters 7-11); 3) key methodologies for studying the role of gut microbiota in cancers (Chapters 12-13); and 4) the potential application of gut microbes for the prevention and treatment of gastrointestinal cancers (Chapters 14-17).

 

The contributors are international experts in molecular and cellular biology, microbiology, metabolomics, bioinformatics and physician scientists to provide in-depth reviews of this subject.

This book provides a rich resource of information on this important topic for graduate students, basic researchers and physicians.

Table of Contents:

Introduction.

- Gut microbiome in health and diseases.

- Microbiome in colorectal cancer.

- Microbiome in gastric cancer.

- Microbiome in liver cancer.

- Virus, fungi and archaea in gastrointestinal cancer.

- Microbial metabolomics in gastrointestinal cancer.

- Diet and gut microbiome in gastrointestinal cancer.

- Diet and gut microbiome in fatty liver and its associated liver cancer.

- Host-microbiome interaction in gastrointestinal cancer.

- Gut microbiome and immune responses in gastrointestinal cancer.

- Animal models in the study of microbiome in gastrointestinal cancer.

- High-throughput sequencing data analyses for microbiome profiling.

- Gut microbiota modulation: probiotics and prebiotics in gastrointestinal cancer.

- Roles of gut microbiota in efficacy of anticancer treatment of gastrointestinal cancer.

- Targeting gut microbiota to treat gastrointestinal cancer.