Neuroglia in Neurodegenerative Diseases

 This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative process, and as such are essential players in a variety of diseases, including Alzheimer’s, Parkinson’s, and Huntington’s.
Intended for researchers and students, the book presents recent advances concerning the biology of neuroglia as well as their interaction with neurons during disease progression. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.

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1.  The Concept of Neuroglia

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2.  Evolution of Neuroglia

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3.  Physiology of Astroglia

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4.  Gliocrine System: Astroglia as Secretory Cells of the CNS

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5.  Physiology of Oligodendroglia

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6.  Physiology of Microglia

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7.  General Pathophysiology of Astroglia

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8.  Neuroglia in Ageing

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9.  Astroglia in Leukodystrophies

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10.  Astrocytes in Motor Neuron Diseases

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11.  Astroglia in Alzheimer’s Disease

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12.  Oligodendroglial Cells in Alzheimer’s Disease

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13.  Microglia in Parkinson’s Disease

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14.  Astrocytes in Huntington’s Disease

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15.  Induced Pluripotent Stem Cell-Derived Astroglia: A New Tool for Research Towards the Treatment of