Oxford Textbook of Sj?gren’s Syndrome (Oxford Textbooks in Rheumatology)

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Description:

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Sj?gren's syndrome is a chronic autoimmune disease which can cause debilitating fatigue and pain. Diagnosis is often challenging due to the variability of symptoms and severity, and a multidisciplinary approach to management and treatment is required, yet there are few comprehensive resources covering everything clinicians need to know. The Oxford Textbook of Sj?gren's Syndrome bridges this gap by offering extensive coverage of system by system manifestations and treatments, as well as practical, evidence-based advice on diagnosing and managing this condition. Bringing together recent advances in research and therapies, this up-to-date guide covers everything clinicians need to know from the fundamental science and clinical characteristics of this condition, to the immunological and biochemical aspects, investigative procedures such as biopsy techniques and imaging modalities, and pharmacological and non-pharmacological interventions.

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Table of Contents:

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Section 1 Introduction

1. 1 Introduction

1. 2 Historical background, classification, and diagnostic criteria

1. 3 Epidemiology and genetics of Sj?gren?s syndrome

Section 2 Basic science

2. 1 Biomarkers in primary Sj?gren?s syndrome

2. 2 Autoantibodies and autoantigens in Sj?gren?s syndrome

2. 3 Stromal cells in Sj?gren?s syndrome

Section 3 Diagnostic investigations

3. 1 Clinical assessment of salivary glands function

3. 2 Salivary gland biopsy?procedure and histopathology

3. 3 Imaging in Sj?gren?s syndrome

Section 4 Head and neck manifestations and clinical management

4. 1 Salivary gland manifestations and management

4. 2 Oral manifestations and management

4. 3 Dental-related disease

Section 5 Ocular manifestations and management

5. 1 Ocular manifestations of Sj?gren?s syndrome

5. 2 A therapeutic strategy for Sj?gren?s syndrome dry eye

Section 6 Systemic manifestations

6. 1 Cutaneous involvement and management of Sj?gren?s syndrome

6. 2 Musculoskeletal disease?presentation and management

6. 3 Renal involvement in primary Sj?gren?s syndrome

6. 4 Gastrointestinal disease in Sj?gren?s syndrome

6. 5 Neurological complications of Sj?gren?s syndrome

6. 6 Cardiovascular and lung manifestations of Sj?gren?s syndrome

6. 7 Haematological manifestations of Sj?gren?s syndrome

6. 8 Fatigue in Sj?gren?s syndrome

6. 9 Nonpharmacological interventions for the management of fatigue and constitutional symptoms in Sj?gren?s syndrome

6. 10 Gynaecologic and obstetric aspects in Sj?gren?s syndrome

6. 11 Sj?gren?s syndrome?associated lymphoma

Section 7 Juvenile and young adult

7. 1 Juvenile- and young adult?onset Sj?gren?s syndrome

Section 8 Sj?gren?s mimics and overlaps

8. 1 Mimics of Sj?gren?s syndrome

8. 2 Sj?gren?s syndrome overlaps

Section 9 Experimental treatments, emerging therapies, and the future

9. 1 Experimental therapies in primary Sj?gren?s syndrome

9. 2 Sj?gren?s syndrome?summary of clinical management

Index

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