Precision Pathology of Cancer: From Basic Concept to Clinical Practice

Precision pathology of cancer is a new frontier - a systemic diagnostic approach to provide specific therapeutic targets and genetic and metabolic information for the treatment of patients. Not only are cancers extremely diverse but there is also heterogenetic variation among patients with the same cancer; owing to differences in genetic makeup and metabolic levels, a drug may work in one patient but be toxic in another. This text covers both basic concepts (the role of the precision pathologist, ethical issues, molecular basis, tools used in precision pathology, and specimen procurement) and clinical practice (the precise genes/pathways, ongoing clinical trials, therapeutics, pharmacogenomics, pharmacoproteomics, and pharmacometabolomics) in precision pathology of cancer. Covers both the conceptual bases and the clinical applications Enables pathologists, haematologists, and medical oncologists to apply Precision Pathology to their daily clinical practice Covers the whole range of cancers in practical detail

Contents:

Preface

Editors

Contributors

1. Precision Pathology

2. The Role of Precision Pathologists

3. Ethical Issues in Precision Pathology

4. Molecular Basis of Precision Pathology

5. Tools in Precision Pathology

6. Specimen Acquisition

7. Skin Cancers

8. Bone and Soft Tissue Tumors

9. Primary Central Nervous System Tumors

10. Head and Neck Cancers

11. Lung Cancers

12. Mesothelioma

13. Breast Cancers

14. Gastrointestinal System Carcinomas

15. Hepatobiliary and Pancreatic Cancers

16. Urinary and Male Genital Tract Tumors

17. Female Genital Tract Tumors

18. Neuroendocrine Neoplasms

19. Myeloid Neoplasms

20. Lymphoid Neoplasms

Index