Prenatal Diagnostic Testing for Genetic Disorders

Makes the state of the art of NIPT after 10 years from its introduction

Presents advantages, shortcomings, cost-benefits and challenges

Written by international experts in the field

About this book:

This comprehensive volume covers all aspects of the revolution in prenatal diagnosis brought about by the introduction of non-invasive prenatal testing (NIPT), which primarily relies on the detection of free fetal DNA circulating in maternal blood from the early stages of pregnancy.

The book explores the potential of NIPT to provide full genome screening of the fetus and identify many common or rare disorders.

The counseling process, as well as the limitations and pitfalls of various techniques used to perform NIPT, are described, evaluated, and critically discussed by renowned international experts.

The book also compares the new technology with more conventional tests, preimplantation diagnosis, and the invasive procedures currently in use.

This book will be a valuable resource for gynecologists, obstetricians, geneticists, maternal-fetal medicine specialists, pathologists, neonatologists, reproductive medicine specialists, midwives, and anyone interested in prenatal genetic diagnosis.

Table of contents (26 chapters)

Front Matter

Pages i-xvii

Introduction

Clinical Genetics

Noninvasive Diagnosis

Clinical Setting and Trends