Skin Aging & Cancer: Ambient UV-R Exposure

This book summarizes the potent effect of ultraviolet radiation (UVR) on the photoaging and cancer formation.

Skin is the largest human organ which continually reconstructs itself to ensure its viability, integrity, and ability to provide protection for the body.

This protection can be compromised by the aging of the skin which ultimately promotes skin inflammation, impaired wound repair, and increased risk of skin cancer.

The book entails mechanistic insights into the UVR-induced immunomodulation and DNA damage in the skin to delineate the pathogenesis, and develop novel ways for prevention of photoaging of the skin cells.

It also elucidates the potential of nanotechnology in the treatment of skin cancer.

Further, it discusses the bioinformatics approaches to understand the molecular mechanism of photoaging and cancer formation.

·  Skin Anatomy and Morphology

·  Understanding Cellular and Molecular Events of Skin Aging and Cancer: An Integrative Perspective

·  Human Skin Stem Cells, Aging, and Possible Antiaging Strategies

·  UVR-Induced Skin Cancer

·  Ultraviolet Radiation-Induced Immunomodulation: Skin Ageing and Cancer

·  UVR and Role of Pigmentation in Skin Aging and Cancer

·  UVR and Vitamin D Synthesis

·  Chemiexcitation of Melanin and Melanoma Pathogenesis

·  Future Prospective of Nanotechnology in Skin Cancer Therapeutics

·  Bioinformatics in Skin Cancer: A System Biology Approach to Understanding the Molecular Mechanisms and It’s Regulations

·  UV-R Interaction with Skin: Cases of Study

·  Monitoring the Genotoxic Potential of Sunlight and DNA Photoprotection of Sunscreen