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Studies in Natural Products Chemistry

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Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin.

It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines.

Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound.

The complete synthesis of erythromycin A is also covered.

The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed.

The development of an A-Ring annulation strategy for taxane synthesis is also presented.

A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes.

The book can provide useful information to chemists, biologists, students, and researchers.

Detalii
  • ISBN: 9780444893666
  • Autori: Atta-ur Rahman
  • Limba: Engleză
  • An apariție: 1993
  • Coperta: Hardcover
  • Editura: Elsevier Science
  • Nr. pagini: 548
  • Greutate: 1140gr
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