Tietz Textbook of Laboratory Medicine

Description:

Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult - featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more.

Features:

• Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment.
• Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests.
• Expert, internationally recognized chapter authors present guidelines representing different practices and points of view.
• Analytical criteria focus on the medical usefulness of laboratory procedures.
• Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world.
• Expert Consult provides the entire text as a fully searchable eBook, and includes regular content updates, animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more.

New To This Edition:

• NEW! 19 additional chapters highlight various specialties throughout laboratory medicine.
• NEW! Updated, peer-reviewed content provides the most current information possible.
• NEW! The largest-ever compilation of clinical cases in laboratory medicine is included on Expert Consult.
• NEW! Over 100 adaptive learning courses on Expert Consult offer the opportunity for personalized education.

Table Of Contents:

SECTION I: BASICS OF LABORATORY MEDICINE

1. Laboratory Medicine

2. Statistical Methodologies in Laboratory Medicine: Analytical and Clinical Evaluation of Laboratory Tests Medical Laboratory

3. Governance, Risk, and Quality Management in the

4. Specimen Collection and Processing

5. Preanalytical Variation and Pre-Examination Processes

6. Quality Control of the Analytical Examination Process

7. Standardization and Harmonization of Analytical Examination Results

8. Biological Variation and Analytical Performance Specifications

9. Establishment and Use of Reference Intervals

10. Evidence-Based Laboratory Medicine

11. Biobanking

12. Laboratory Support of Pharmaceutical, In Vitro Diagnostics, and Epidemiologic Studies

13. Machine Learning and Big Data in Laboratory Medicine

14. Laboratory Stewardship and Test Utilization

15. Principles of Basic Techniques and Laboratory Safety
SECTION II: ANALYTICAL TECHNIQUES

16. Optical Techniques

17. Electrochemistry and Chemical Sensors

18. Electrophoresis

19. Chromatography

20. Mass Spectrometry

21. Sample Preparation for Mass Spectrometry

22. MALDI-TOF Mass Spectrometry Applications in Infectious Diseases

23. Development and Validation of Small Molecule Analytes by Liquid Chromatography-Tandem Mass Spectrometry

24. Proteomics

25. Enzyme and Rate Analysis

26. Immunochemical Techniques

27. Microfabrication and Microfluidics and Their Application in Clinical Diagnostics

28. Cytometry

29. Automation in the Clinical Laboratory

30. Point-of-Care Testing
SECTION III: CLINICAL CHEMISTRY-ANALYTES

31. Amino Acids, Peptides, and Proteins

32. Serum Enzymes

33. Tumor Markers

34. Kidney Function Tests

35. Carbohydrates

36. Lipids and Lipoproteins

37. Electrolytes and Blood Gases

38. Hormones

39. Vitamins and Trace Elements

40. Iron Metabolism

41. Porphyrins and the Porphyrias

42. Therapeutic Drugs and Their Management

43. Clinical Toxicology

44. Toxic Elements

45. Body Fluids
SECTION IV: CLINICAL CHEMISTRY-PATHOPHYSIOLOGY

46. Nutrition: Laboratory and Clinical Aspects

47. Diabetes Mellitus

48. Cardiac Function

49. Kidney Disease

50. Disorders of Water, Electrolytes, and Acid-Base Metabolism

51. Liver Disease

52. Gastric, Intestinal, and Pancreatic Function

53. Monoamine-Producing Tumors

54. Bone and Mineral Metabolism

55. Pituitary Function and Pathophysiology

56. Adrenal Cortex

57. Thyroid Disorders

58. Reproductive Endocrinology and Related Disorders

59. Pregnancy and Its Disorders
SECTIONV:GENETICMETABOLICDISORDERS

60. NewbornScreeningandInbornErrorsofMetabolism

61. Inborn Errors of Metabolism: Disorders of Complex Molecules
SECTION VI: MOLECULAR DIAGNOSTICS

62. Principles of Molecular Biology

63. Nucleic Acid Isolation

64. Nucleic Acid Techniques

65. Genomes,Variants,andMassivelyParallelMethods

66. Clinical Genome Sequencing

67. Molecular Microbiology

68. Genetics

69. Solid Tumors

70. Hematopathology

71. Circulating Tumor Cells and Circulating Nucleic Acids in Oncology

72. CirculatingNucleicAcidsforPrenatalDiagnostics

73. Pharmacogenetics
SECTION VII: HEMATOLOGY AND COAGULATION

74. Automated Hematology

75. LeukocyteMorphologyinBloodandBoneMarrow

76. Red Blood Cell Morphology and Indices: The Clinical Chemistry Interface

77. Hemoglobin and Hemoglobinopathies

78. Enzymes of the Red Blood Cell

79. Physiology of Hemostasis

80. Platelets and von Willebrand Factor

81. Coagulation, Anticoagulation, and Fibrinolysis
SECTION VIII: MICROBIOLOGY

82. Introduction to Infectious Diseases

83. The Role of the Clinical Laboratory in Infection
Prevention and Antimicrobial Stewardship

84. Bacteriology

85. Antimicrobial Susceptibility Testing

86. Mycobacteriology

87. Mycology

88. Parasitology

89. Virology
SECTION IX: TRANSFUSION MEDICINE

90. Blood Group Systems and Pretransfusion Testing

91. Blood Components, Product Modifications, and Blood Donor Screening

92. Indications for Transfusion: RBCs, Platelets, Plasma,and Cryoprecipitate

93. Transfusion Reactions and Adverse Events Associated With Transfusion
SECTION X: CLINICAL IMMUNOLOGY

94. Systemic Autoimmune Disease

95. Transplant, Solid Organ

96. Hematopoietic Cell Transplantation

97. Transplant Compatibility Testing

98. Monoclonal Antibody Therapeutics and Immunogenicity

99. Allergy Testing

100. Primary Immunodeficiencies and Secondary Immunodeficiencies
APPENDICES
Appendix A: Reference Information for the Clinical Laboratory
Appendix B: Answers to Multiple Choice Questions